Marius ILIÉ, Program Director, M.D., Ph.D., Head of Department of Laboratory of Clinical and Experimental Pathology (LPCE) Pasteur Hospital, Nice
Marius ILIÉ is Professor of Pathology at the Nice Medical School, Université Côte d’Azur and Surgical Pathologist at the Clinical and Experimental Pathology Laboratory, Nice University Hospital. He has special interest in thoracic pathology, molecular pathology and Biobanking. He has a longstanding interest and expertise in the area of prognostic and predictive biomarkers in thoracic oncology (Institute for Research on Cancer and Ageing) as well as in Biobanking (Hospital-Integrated Biobank, BB-0033-00025). He has contributed to several publications in the field of biomedical research and biorepository science (190 peer-reviewed articles listed in PubMed, h-index: 47). He is also dedicated to teaching as Director of the European Masters in Molecular Pathology (MSc EMMP, EUMS; https://univ-cotedazur.eu/msc/european-msc-molecular-pathology).
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Pedagogic Team
Doctor Georges DAGHER
Georges Dagher is currently an Emeritus Senior Researcher at the National Institute for Health and Research, (Inserm), Paris; Visiting Professor at Faculty of Medicine, Milano-Bicocca University, Italy; He is also the CEO of a private society, Paradigm 66.
He was an Honorary professor at Stem Laboratory, Chinese Academy of Sciences, Beijing; and also a visiting Professor at Graz Medical University, Austria.
Georges Dagher accomplished most of his career in pathophysiological and clinical research at Necker Hospital (1979-1984), College de France (1985-1993) and Faculty of medicine Broussais-Hotel Dieu (1994-2004). He joined the Physiological Laboratory (Cambridge, UK) for a postdoctoral fellowship (1983-1985) and was a visiting researcher to Biophysics & Physiological laboratory (Harvard Medical School, Boston, US, 1982, 1984), Cleveland Clinic (1986) and Farmitalia (1982). He published about 100 papers in international peer-reviewed journals on hypertension, arterial hypertrophy, obesity and lipid metabolism, manic depression, renal physiology and transmembrane ion transport.
He was the Director of the BIOBANQUES infrastructure, a French infrastructure that networks 85 biobanks and the vice chair of BBMRI-ERIC a pan European Infrastructure that networks more than 500 biobanks in Europe. Prior to this role, He acted as the Director of clinical research infrastructures at Inserm and Deputy Director of the department of clinical research at the Public Health Institute, Inserm, France.
He is the Convenor of a Working Group Biobanking and Biological Ressources at the ISO Technical Committee “Biotechnology” (ISO/TC 276) and member of several Technical Committees at International Standard Organisation: Medical laboratory (ISO/TC 212), Food Products (ISO/TC 34); Health informatics (ISO/TC 215). He actively contributed to the publication of 40 International standards related to the biomedical field, laboratory analysis and testing, and health informatics. He is also a reference expert to more than 200 standards in these fields (work in in progress). He is also affiliated to ISO CASCO and ISO REMCO.
Previously, he chaired the elaboration of the NF S96-900 French standard for biobanks (2008) and contributed to the OECD best practice guidelines for biological resource centres and the OECD guidelines on human biobanks and genetic databases (2006-2009).
He was a delegate of several French institutions to European and international committees (OECD, ESF, ERA, ALLEA, EASAC…) and of a number of expert committees focusing on issues related to biobanks within Europe and internationally. He was an expert to the Austrian Federal ministry of science and research (BMWF) and Institut de Recherche sur le Cancer (Maroc), National biobank infrastructure in Italy and Austria and was an expert to the Flemish ministry of research, Quebec "Fond Scientifique de la Recherche", Swiss National Science Foundation.
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Pedagogic Team
Doctor Bruno CLEMENT
After completing a PhD in cellular and molecular biology, Bruno Clément spent a post-doc period at the NIH in Bethesda (USA). In 1985, he was recruited by Inserm in the “Liver research unit” in Rennes. In 1992, he became research director of the “Microenvironment and Tumor Progression” team at Inserm U-620. Head of the Inserm “Liver, Metabolism and Cancer” unit in 2010, he was appointed director of the “Nutrition, Metabolism and Cancer” Institute in 2017 (Inserm-Inrae-University of Rennes). Most of his work focuses on liver pathophysiology, chronic liver diseases, and hepatic carcinogenesis. His main scientific contributions include the characterization of hepatic fibrosis and its cellular origin; the reversibility of hepatic fibrosis; the role of the microenvironment and tissue remodeling in hepatocyte function, in fibrosis/cirrhosis, and in the onset and progression of hepatocellular carcinoma; cell engineering: 2D and 3D (organoids), bioartificial liver; selective cell irradiation in the treatment of hepatocellular carcinoma. Counselor at the Ministry of Research in 1998, then Deputy Director of the Bioengineering Department in 2000, Bruno Clément participated in the implementation of the Innovation Act of July 1999 by launching incentives for the development of biotechnologies in the field of health and the national program for biological resource centers (incentives, parliamentary report, revision of bioethics laws in 2004, chairmanship of the National Advisory Committee for BRCs). He was member of several international committees on biobanks: OECD (head of delegation), 7th PCRDT, NIH, WHO, Council of Europe, International Network of Pasteur Institutes, AFNOR, ISO. From 2003 to 2007, Bruno Clément was advisor to the Director General of Inserm for biotechnologies and biobanks, and scientific director of Inserm-Transfert. He was scientific director of the National Biobank Infrastructure from 2011 to 2016. Bruno Clément is currently member of the Inserm Ethics Committee (IRB-CEEI) and full member of the French National Academy of Medicine.
